Clinical characteristics and novel mutations of omicron subvariant XBB in Tamil Nadu, India - a cohort study.

ABSTRACT:

Background

Despite the continued vaccination efforts, there had been a surge in breakthrough infections, and the emergence of the B.1.1.529 omicron variant of SARS-CoV-2 in India. There is a paucity of information globally on the role of newer XBB variants in community transmission. Here, we investigated the mutational patterns among hospitalised patients infected with the XBB omicron sub-variant, and checked if there was any association between the rise in the number of COVID-19 cases and the observed novel mutations in Tamil Nadu, India.

Methods

Nasopharyngeal and oropharyngeal swabs, collected from symptomatic and asymptomatic COVID-19 patients were subjected to real-time PCR followed by Next Generation Sequencing (NGS) to rule out the ambiguity of mutations in viruses is

SUBMITTER: Selvavinayagam ST 

PROVIDER: S-EPMC10709680 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature