American Society of Hematology 2023 guidelines for management of venous thromboembolism: thrombophilia testing.

ABSTRACT: Hereditary and acquired thrombophilia are risk factors for venous thromboembolism (VTE). Whether testing helps guide management decisions is controversial. These evidence-based guidelines from the American Society of Hematology (ASH) intend to support decision making about thrombophilia testing. ASH formed a multidisciplinary guideline panel covering clinical and methodological expertise and minimizing bias from conflicts of interest. The McMaster University GRADE Centre provided logistical support, performed systematic reviews, and created evidence profiles and evidence-to-decision tables. The Grading of Recommendations Assessment, Development, and Evaluation approach (GRADE) was used. Recommendations were subject to public comment. The panel agreed on 23 recommendations regarding thrombo

SUBMITTER: Middeldorp S 

PROVIDER: S-EPMC10709681 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature