Predicting the hyperelastic properties of alginate-gelatin hydrogels and 3D bioprinted mesostructures.

ABSTRACT: Additive manufacturing has been widely used in tissue engineering, as 3D bioprinting enables fabricating geometrically complicated replacements for different tissues and organs. It is vital that the replacement mimics the specific properties of native tissue and bears the mechanical loading under its physiological conditions. Computational simulations can help predict and tune the mechanical properties of the printed construct-even before fabrication. In this study, we use the finite element (FE) method to predict the mechanical properties of different hydrogel mesostructures fabricated through various print patterns and validate our results through corresponding experiments. We first quantify the mechanical properties of alginate-gelatin hydrogels used as matrix material through an invers

SUBMITTER: Soufivand AA 

PROVIDER: S-EPMC10710406 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature