Abscisic acid-mediated cytosolic Ca²⁺ modulates triterpenoid accumulation of Ganoderma lucidum.

ABSTRACT: Ganoderma lucidum is a mushroom widely used for its edible and medicinal properties. Primary bioactive constituents of G. lucidum are ganoderic triterpenoids (GTs), which exhibit important pharmacological activity. Abscisic acid (ABA), a plant hormone, is associated with plant growth, development, and stress responses. ABA can also affect the growth, metabolism, and physiological activities of different fungi and participates in the regulation of the tetracyclic triterpenes of some plants. Our findings indicated that ABA treatment promoted GT accumulation by regulating the gene expression levels (squalene synthase (sqs), 3-hydroxy-3-methylglutaryl-CoA reductase (hmgr), and lanosterol synthase (ls)), and also activated cytosolic Ca²⁺ channels. Furthermore, under ABA mediation, ex

SUBMITTER: Cui M 

PROVIDER: S-EPMC10710909 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature