Association of serum phosphate and changes in serum phosphate with 28-day mortality in septic shock from MIMIC-IV database.

ABSTRACT: This study aimed to investigate the relationship between serum phosphate levels, changes in serum phosphate levels, and 28-day mortality in patients with septic shock. In this retrospective study, data were collected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database between 2008 and 2019. Patients were divided into three groups according to the tertiles of serum phosphate levels. Kaplan-Meier curves and log-rank test analyses were used for survival analysis. Multivariate logistic regression, and restricted cubic spline (RCS) curve were used to explore the association between serum phosphate, delta serum phosphate levels and 28-day mortality. In total, 3296 patients with septic shock were included in the study, and the 28-day mortality was 30.0%. Serum phosphate le

SUBMITTER: Nan W 

PROVIDER: S-EPMC10711004 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature