The value of multiparametric MRI radiomics in predicting IDH genotype in glioma before surgery.

ABSTRACT:

Objective

To explore the value of multiparametric magnetic resonance imaging(MRI) radiomics in the preoperative prediction of isocitrate dehydrogenase (IDH) genotype for gliomas.

Methods

The preoperative routine MRI sequences of 114 patients with pathologically confirmed grade II-IV gliomas were retrospectively analysed. All patients were randomly divided into training cohort(n=79) and validation cohort(n=35) in the ratio of 7:3. After feature extraction, we eliminated covariance by calculating the linear correlation coefficients between features, and then identified the best features using the F-test. The Logistic regression was used to build the radiomics model and the clinical model, and to build the combined model. Assessment of these models by subject operating characte

SUBMITTER: Liang Y 

PROVIDER: S-EPMC10711053 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature