Prospective observational study of baloxavir marboxil in adults and adolescents with uncomplicated influenza from China.

ABSTRACT:

Introduction

There are limited data on the efficacy of baloxavir marboxil (baloxavir) versus oseltamivir in Chinese patients with influenza A.

Methods

This study is an observational real-world investigation encompassing 246 patients (baloxavir, n = 147; oseltamivir, n = 99) confirmed positive for influenza A. The choice between baloxavir and oseltamivir antiviral treatments was determined collaboratively by the clinician and the patient. A thorough comparative analysis was undertaken between the two groups, examining parameters such as the duration of fever and symptoms, viral load dynamics, lymphocyte changes, and enhancements in health-related quality of life (QoL).

Results

No significant differences were observed in demographic data between the two gr

SUBMITTER: Liao G 

PROVIDER: S-EPMC10711061 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature