MiRGediNET: A comprehensive examination of common genes in miRNA-Target interactions and disease associations: Insights from a grouping-scoring-modeling approach.

ABSTRACT: In the broad and complex field of biological data analysis, researchers frequently gather information from a single source or database. Despite being a widespread practice, this has disadvantages. Relying exclusively on a single source can limit our comprehension as it may omit various perspectives that could be obtained by combining multiple knowledge bases. Acknowledging this shortcoming, we report on miRGediNET, a novel approach combining information from three biological databases. Our investigation focuses on microRNAs (miRNAs), small non-coding RNA molecules that regulate gene expression post-transcriptionally. We delve deeply into the knowledge of these miRNA's interactions with genes and the possible effects these interactions may have on different diseases. The scientific communit

SUBMITTER: Qumsiyeh E 

PROVIDER: S-EPMC10711121 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature