Investigating antiarthritic potential of polyherbal emulgel.

ABSTRACT:

Background

Rheumatoid arthritis (RA) is an inflammation of joints with increased cellularity of synovial tissue. Allopathic drugs possess several adverse effects, which have led to increase in the utilization of herbal medicines. Polyherbal emulgel resolves the bioavailability issue associated with hydrophobic drugs and can be used effectively in the treatment of RA.

Objectives

The present study aimed at the formulation of polyherbal emulgel, and evaluation of in vitro anti-inflammatory activity and in vivo antiarthritic activity.

Methods

Seven emulgels F-1 to F-7 were optimally formulated. In vitro anti-inflammatory activity was determined using protein denaturation method employing Diclofenac sodium as the standard. In antiarthritic study Complete Freund's Adjuvant

SUBMITTER: Rana N 

PROVIDER: S-EPMC10711174 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature