Hematin and Cu^II control generations of hydroperoxyl and superoxide radicals to activate galactose oxidase for 5-hydroxymethylfurfural conversion.

ABSTRACT: We present a significant finding that Cu(II) ions can activate hematin (Hem) to generate more HOO⋅ and O₂^⋅- radicals from the decomposition of H₂O₂. Galactose oxidase (GO) and hematin have been simultaneously immobilized by coordinating to Cu(II) ions (GO&Hem@Cu(II)). The radicals HOO⋅ and O₂^⋅- and dioxygen O₂ can be in situ generated from the byproduct H₂O₂ by the Cu(II)-activated hematin. Ample experimental evidence supports the discovery that the immobilized GO is reactivated by the in situ generated HOO⋅ and O₂^⋅-. For the conversion of 100 mM 5-hydroxymethylfurfural (HMF) in water, GO&Hem@Cu(II) (0.8 mg/mL GO encapsulated) has achieved a 99.5% conversio

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10711400 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature