Occurrence of homologs of the Escherichia coli lytB gene in gram-negative bacterial species.

ABSTRACT: The Escherichia coli LytB protein regulates the activity of guanosine 3',5'-bispyrophosphate synthetase I (RelA). A Southern blot analysis of chromosomal DNA with the E. coli lytB gene as a probe revealed the presence of lytB homologs in all of the gram-negative bacterial species examined but not in gram-positive species. The lytB homologs from Enterobacter aerogenes and Pseudomonas fluorescens complemented the E. coli lytB44 mutant allele.

SUBMITTER: Potter S 

PROVIDER: S-EPMC107115 | biostudies-literature | 1998 Apr

REPOSITORIES: biostudies-literature