Histone retention preserves epigenetic marks during heat stress-induced transcriptional memory in plants.

ABSTRACT: Plants often experience recurrent stressful events, for example, during heat waves. They can be primed by heat stress (HS) to improve the survival of more severe heat stress conditions. At certain genes, sustained expression is induced for several days beyond the initial heat stress. This transcriptional memory is associated with hyper-methylation of histone H3 lysine 4 (H3K4me3), but it is unclear how this is maintained for extended periods. Here, we determined histone turnover by measuring the chromatin association of HS-induced histone H3.3. Genome-wide histone turnover was not homogenous; in particular, H3.3 was retained longer at heat stress memory genes compared to HS-induced non-memory genes during the memory phase. While low nucleosome turnover retained H3K4 methylation, methylatio

SUBMITTER: Pratx L 

PROVIDER: S-EPMC10711655 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature