Association between the homeostasis model assessment of insulin resistance and coronary artery calcification: a meta-analysis of observational studies.

ABSTRACT:

Background

Insulin resistance (IR), a risk factor for cardiovascular diseases, has garnered significant attention in scientific research. Several studies have investigated the correlation between IR and coronary artery calcification (CAC), yielding varying results. In light of this, we conducted a systematic review to investigate the association between IR as evaluated by the homeostasis model assessment (HOMA-IR) and CAC.

Methods

A comprehensive search was conducted to identify relevant studies in PubMed, Embase, Scopus, and Web of Science databases. In addition, preprint servers such as Research Square, BioRxiv, and MedRxiv were manually searched. The collected data were analyzed using either fixed or random effects models, depending on the heterogeneity observed among the

SUBMITTER: Li L 

PROVIDER: S-EPMC10711676 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature