The association between dapagliflozin use and the risk of post contrast acute kidney injury in patients with type 2 diabetes and chronic kidney disease: a propensity-matched analysis.

ABSTRACT: Introduction This study aimed to investigate the effect of dapagliflozin in preventing post contrast acute kidney injury (PC-AKI) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) who underwent an elective coronary procedure. Methods Data of patients with T2DM and CKD undergoing an elective coronary procedure at Civil Aviation General Hospital from October 2020 to April 2023, were collected from the electronic medical records. Based on dapagliflozin usage, patients were classified as dapagliflozin users and non-users. 1:1 nearest-neighbor propensity matching was performed to compare dapagliflozin users with non-users. The primary endpoint was the first PC-AKI observed. Univariate and multivariate COX regression models were used to determine the independent risk/preve

SUBMITTER: Liu T 

PROVIDER: S-EPMC10711763 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature