Prediction of T staging in PI-RADS 4-5 prostate cancer by combination of multiparametric MRI and ⁶⁸Ga-PSMA-11 PET/CT.

ABSTRACT:

Background

In this study, we explored the diagnostic performances of multiparametric magnetic resonance imaging (mpMRI), ⁶⁸ Ga-PSMA-11 PET/CT and combination of ⁶⁸ Ga-PSMA-11 PET/CT and mpMRI (mpMRI + PET/CT) for extracapsular extension (ECE). Based on the analyses above, we tested the feasibility of using mpMRI + PET/CT results to predict T staging in prostate cancer patients.

Methods

By enrolling 75 patients of prostate cancer with mpMRI and ⁶⁸ Ga-PSMA-11 PET/CT before radical prostatectomy, we analyzed the detection performances of ECE in mpMRI, ⁶⁸ Ga-PSMA-11 PET/CT and mpMRI + PET/CT on their lesion images matched with their pathological sample images layer by layer through receiver operating characteristics (ROC) analysis. By

SUBMITTER: Ding Y 

PROVIDER: S-EPMC10712094 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature