Protective effects of Salvianic acid A against multiple-organ ischemia-reperfusion injury: a review.

ABSTRACT: Ischemia-reperfusion (I/R) injury refers to a new injury caused by reperfusion after the restoration of ischemic tissue or organ blood supply. Salvianic acid A (danshensu) is a primary active ingredient extracted from Salvia miltiorrhiza. It has a protective function against I/R injury in the cardiovascular system, brain, liver, kidney, gastrointestinal tract, and other organs. This article reviews evidence of the protective effects of Salvianic acid A and its potential mechanisms of action in organ I/R injury protection. The aim of this review is to investigate the role of Salvianic acid A in the treatment of I/R injury, providing a reference resource that could facilitate subsequent studies.

SUBMITTER: Yang S 

PROVIDER: S-EPMC10712837 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature