Pubertal maturation and timing effects on resting state electroencephalography in autistic and comparison youth.

ABSTRACT: Autistic and comparison individuals differ in resting-state electroencephalography (EEG), such that sex and age explain variability within and between groups. Pubertal maturation and timing may further explain variation, as previous work has suggested alterations in pubertal timing in autistic youth. In a sample from two studies of 181 autistic and 94 comparison youth (8 years to 17 years and 11 months), mixed-effects linear regressions were conducted to assess differences in EEG (midline power for theta, alpha, and beta frequency bands). Alpha power was analyzed as a mediator in the relation between pubertal maturation and timing with autistic traits in the autistic groups to understand the role of puberty in brain-based changes that contribute to functional outcomes. Individuals advanced

SUBMITTER: Rea HM 

PROVIDER: S-EPMC10713348 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature