Prevention of activated brown adipose tissue on ¹⁸F-FDG-PET scans of young lymphoma patients: results of an ancillary study within the EuroNet-PHL-C2 trial.

ABSTRACT: Activated brown fat (aBAT) is known to affect the evaluation of ¹⁸F-FDG PET scans, especially in young patients. The aim of this study was to determine factors influencing the occurrence of aBAT, and to investigate the effectiveness of the two preventive measures, warming and beta-blocker (propranolol) administration. Five-hundred-twenty-eight ¹⁸F-FDG-PET scans of 241 EuroNet-PHL-C2 trial patients from 41 nuclear medicine departments in Germany and Czech Republic were screened for aBAT. The occurrence of aBAT was analyzed with patient characteristics (age, sex, body mass index, predisposition to aBAT), weather data at the day of ¹⁸F-FDG PET scanning as well as the preventive measures taken. Potentially important factors from univariate analyses were include

SUBMITTER: Potzsch C 

PROVIDER: S-EPMC10713612 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature