Sulforaphane as a potential modifier of calorie-induced inflammation: a double-blind, placebo-controlled, crossover trial.

ABSTRACT:

Background and aims

Observational data indicate that diets rich in fruits and vegetables have a positive effect on inflammatory status, improve metabolic resilience and may protect against the development of non-communicable diseases. Nevertheless, experimental evidence demonstrating a causal relationship between nutrient intake (especially whole foods) and changes in metabolic health is scarce. This study investigated the pleiotropic effects of sulforaphane from broccoli sprouts, compared to pea sprouts, on biomarkers of endothelial function, inflammation and metabolic stress in healthy participants subjected to a standardized caloric challenge.

Methods

In this double-blind, crossover, randomized, placebo-controlled trial 12 healthy participants were administered 16 g brocc

SUBMITTER: van Steenwijk HP 

PROVIDER: S-EPMC10713815 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature