Phylogenetic Inference of Homologous/Orthologous Genes Among Distantly Related Plants.

ABSTRACT: The recent surge in plant genomic and transcriptomic data has laid a foundation for reconstructing evolutionary scenarios and inferring potential functions of key genes related to plants' development and stress responses. The classical scheme for identifying homologous genes is sequence similarity-based searching, under the crucial assumption that homologous sequences are more similar to each other than they are to any other non-homologous sequences. Advances in plant phylogenomics and computational algorithms have enabled us to systemically identify homologs/orthologs and reconstruct their evolutionary histories among distantly related lineages. Here, we present a comprehensive pipeline for homologous sequences identification, phylogenetic relationship inference, and potential functional

SUBMITTER: Xu Z 

PROVIDER: S-EPMC10714154 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature