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The first fungi: mode of delivery determines early life fungal colonization in the intestine of preterm infants.


ABSTRACT: Aim: The role of intestinal fungi in human health and disease is becoming more evident. The mycobiota composition and diversity of preterm infants is affected by interactions with bacteria and clinical variables. In this study, we aimed to characterize the composition and the diversity of the preterm infant mycobiota and the effect of clinical variables on it in the first six postnatal weeks. Methods: Preterm infants (n = 50) and full-term infants (n = 6) admitted to Isala Women and Children's hospital (Zwolle, The Netherlands) who were born during 24-36 or 37-40 weeks of gestation, respectively, were included in this study. Feces were collected during the first six postnatal weeks (n = 109) and their mycobiota composition and diversity were characterized

SUBMITTER: Henderickx JGE 

PROVIDER: S-EPMC10714301 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature