Genetic analysis of the blood transcriptome of young healthy pigs to improve disease resilience.

ABSTRACT:

Background

Disease resilience is the ability of an animal to maintain productive performance under disease conditions and is an important selection target. In pig breeding programs, disease resilience must be evaluated on selection candidates without exposing them to disease. To identify potential genetic indicators for disease resilience that can be measured on selection candidates, we focused on the blood transcriptome of 1594 young healthy pigs with subsequent records on disease resilience. Transcriptome data were obtained by 3'mRNA sequencing and genotype data were from a 650 K genotyping array.

Results

Heritabilities of the expression of 16,545 genes were estimated, of which 5665 genes showed significant estimates of heritability (p < 0.05), ranging from 0.05 to 0.90, w

SUBMITTER: Lim KS 

PROVIDER: S-EPMC10714454 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature