Including uncertainty of the expected mortality rates in the prediction of loss in life expectancy.

ABSTRACT:

Purpose

This study introduces a novel method for estimating the variance of life expectancy since diagnosis (LE_C) and loss in life expectancy (LLE) for cancer patients within a relative survival framework in situations where life tables based on the entire general population are not accessible. LE_C and LLE are useful summary measures of survival in population-based cancer studies, but require information on the mortality in the general population. Our method addresses the challenge of incorporating the uncertainty of expected mortality rates when using a sample from the general population.

Methods

To illustrate the approach, we estimated LE_C and LLE for patients diagnosed with colon and breast cancer in Sweden. General population mortality ra

SUBMITTER: Leontyeva Y 

PROVIDER: S-EPMC10714581 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature