Characterizing bacterial and fungal communities along the longitudinal axis of the intestine in cynomolgus monkeys.

ABSTRACT: The gut microbiota develops specialized local communities along the gastrointestinal (GI) tract of the host. Among these microbes, intestinal bacteria and fungi interact closely with the host and play vital roles in their health. However, the gut biogeography of bacteria and fungi has rarely been studied simultaneously, and their correlations have not been reported. In this study, we collected the intestinal luminal contents from different gastrointestinal regions (the ileum, caecum, and colon) of wild-type female cynomolgus monkeys and performed 16S and 18S rRNA gene sequencing to determine the gut biogeography of bacterial and fungal communities. The richness and diversity of bacteria and fungi increased gradually from the small to the large intestine. The bacterial and fungal compositio

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10714780 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature