Targeted metagenomic assessment reflects critical colonization in battlefield injuries.

ABSTRACT:

Importance

Microbial contamination in combat wounds can lead to opportunistic infections and adverse outcomes. However, current microbiological detection has a limited ability to capture microbial functional genes. This work describes the application of targeted metagenomic sequencing to profile wound bioburden and capture relevant wound-associated signatures for clinical utility. Ultimately, the ability to detect such signatures will help guide clinical decisions regarding wound care and management and aid in the prediction of wound outcomes.

SUBMITTER: Kok CR 

PROVIDER: S-EPMC10714869 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature