Sensitive and selective phenol sensing in denitrifying Aromatoleum aromaticum EbN1^T.

ABSTRACT:

Importance

Aromatic compounds are globally abundant organic molecules with a multitude of natural and anthropogenic sources, underpinning the relevance of their biodegradation. A. aromaticum EbN1^T is a well-studied environmental betaproteobacterium specialized on the anaerobic degradation of aromatic compounds. The here studied responsiveness toward phenol in conjunction with the apparent high ligand selectivity (non-promiscuity) of its PheR sensor and those of the related p-cresol (PcrS) and p-ethylphenol (EtpR) sensors are in accord with the substrate-specificity and biochemical distinctiveness of the associated degradation pathways. Furthermore, the present findings advance our general understanding of the substrate-specific regulation of the stra

SUBMITTER: Buschen R 

PROVIDER: S-EPMC10715001 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature