An isothermal CRISPR-based diagnostic assay for Neisseria gonorrhoeae and Chlamydia trachomatis detection.

ABSTRACT:

Importance

A method for Neisseria gonorrhoeae (NG)/Chlamydia trachomatis (CT) detection is developed using multiplex-recombinase polymerase amplification and Cas12a/Cas13a. This method can detect NG and CT simultaneously with high sensitivity and specificity. This method has great potential to be further developed into larger-scale screening and point-of-care testing (POCT).

SUBMITTER: Luo H 

PROVIDER: S-EPMC10715037 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature