Phenotyping children and adolescents with obesity using behavioral, psychological, and familial data.

ABSTRACT:

Objective

This prospective cohort study aimed to empirically derive phenotypes of children and adolescents with overweight and obesity.

Methods

Latent class analyses using Mplus were carried out in the Growing Up Today Study. Information on participants' weight status, disordered eating behaviors, body image and weight concerns, depressive symptoms, and pubertal timing, as well as and maternal weight status, were included in the latent class analyses, which were stratified by sex. Mixed-effects regression was used to examine associations of the obesity phenotypes with adult weight gain, between age 20 and 35 years, independent of weight at beginning of follow-up and duration of follow-up.

Results

Among the girls, four obesity phenotypes were identified: 1) "early pube

SUBMITTER: St Fleur RG 

PROVIDER: S-EPMC10715712 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature