Association of interleukin-13 gene single nucleotide polymorphism rs1800925 with allergic asthma in Asian population: A meta-analysis.

ABSTRACT:

Background

The interleukin-13 (IL-13) gene has been associated with allergic asthma pathogenesis due to its role in IgE synthesis. The IL-13 single nucleotide polymorphism (SNP) rs1800925 has been implicated in exacerbated allergic asthma symptoms in different ethnicities.

Objectives

To determine the association of IL-13 SNP rs1800925 with allergic asthma symptoms in the Asian population.

Methods

Major databases were searched for studies on the association of IL-13 rs1800925 with allergic asthma in various Asian populations published between 2010 and February 2022. The odds ratio with 95% CI was obtained from included studies, and the association was evaluated using different genetic models. Heterogeneity was explored by subgroup analyses and I² stat

SUBMITTER: Gaceja KV 

PROVIDER: S-EPMC10715742 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature