Clinical Features of Heart Failure With Normal Ejection Fraction: Insights From the ASIAN-HF Registry.

ABSTRACT:

Background

Heart failure and left ventricular ejection fraction in the normal range (HFnEF) (left ventricular ejection fraction [LVEF] of ≥55% for men and ≥60% for women) is understudied.

Objectives

The authors aimed to characterize patients with HFnEF compared with those with preserved (≥50%) yet below the normal LVEF.

Methods

In an Asian HF registry, clinical characteristics, echocardiographic features, and outcomes were compared across: 1) HFnEF; 2) heart failure with preserved left ventricular ejection fraction (HFpEF) (LVEF of ≥50%) and below normal LVEF; and 3) community-based controls without HF. Cluster analysis of echocardiographic parameters was performed and validated in an external cohort.

Results

Among 1,765 patients with HFpEF (age 68 ± 12 years;

SUBMITTER: Teramoto K 

PROVIDER: S-EPMC10715881 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature