Reduced myocardial work in asymptomatic heavy alcohol use and its correlation with epicardial adipose tissue volume and serum biomarkers.

ABSTRACT:

Background

It is unclear whether long-term heavy alcohol use leads to early cardiac function decline.

Hypothesis

Long-term heavy alcohol use developed reduced cardiac function in subclinical status by analyzing myocardial work (MW). Epicardial adipose tissue (EAT) volume and serum biomarkers contribute to identify potential factors sensitive in predicting early cardiac function decline.

Methods

We enrolled 31 asymptomatic participants with heavy alcohol use and 33 age and sex-matching nondrinking individuals. Participants underwent echocardiography, MW analysis, EAT volume measurement, serum biochemical examinations, and body composition assessment. We used multivariate linear regression to identify correlation between MW and total cholesterol (TC), EAT volume, and pl

SUBMITTER: Gao C 

PROVIDER: S-EPMC10716317 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature