Risk of new-onset and prevalent disease in chronic rhinosinusitis: A prospective cohort study.

ABSTRACT:

Background

Chronic rhinosinusitis (CRS) is accompanied by burdensome comorbid conditions. Understanding the relative timing of the onset of these conditions could inform disease prevention, detection, and management.

Objective

To evaluate the association between CRS and new-onset and prevalent asthma, noncystic fibrosis bronchiectasis (NCFBE), chronic obstructive pulmonary disease (COPD), gastroesophageal reflux disease (GERD), and obstructive sleep apnea (OSA).

Methods

We conducted a prospective cohort study among primary care patients using a detailed medical and symptom questionnaire in 2014 and again in 2020. We used questionnaire and electronic health record (EHR) data to determine CRS status: CRS_SE (moderate to severe symptoms with EHR evidence), CRS<

SUBMITTER: Hirsch AG 

PROVIDER: S-EPMC10716683 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature