A systematic review of pregnancy-related clinical intervention of drug regimens due to pharmacokinetic reasons.

ABSTRACT:

Background and objective

Published works have discussed the pharmacokinetic interactions of drugs with pregnancy, but none comprehensively identify all the approved United States Food and Drug Administration (FDA) and European Medicines Administration (EMA) drugs that have a pregnancy-related intervention. The objective of this systematic review is to comprehensively identify medications that have clinically meaningful interventions due to pharmacokinetic reasons.

Methods

An in-depth search of clinical data using the PDR3D: Reed Tech Navigator™ for Drug Labels was conducted from 1 June to 12 August 2022. The PDR3D was analyzed using the search terms "pregnant" and "pregnancy" within the proper label section. Regarding the US labels, the terms were searched under the "dosage

SUBMITTER: Borda LA 

PROVIDER: S-EPMC10716708 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature