Antiplatelet Therapy, Abdominal Aortic Aneurysm Progression, and Clinical Outcomes.

ABSTRACT:

Importance

Preclinical studies suggest a potential role for aspirin in slowing abdominal aortic aneurysm (AAA) progression and preventing rupture. Evidence on the clinical benefit of aspirin in AAA from human studies is lacking.

Objective

To investigate the association of aspirin use with aneurysm progression and long-term clinical outcomes in patients with AAA.

Design, setting, and participants

This was a retrospective, single-center cohort study. Adult patients with at least 2 available vascular ultrasounds at the Cleveland Clinic were included, and patients with history of aneurysm repair, dissection, or rupture were excluded. All patients were followed up for 10 years. Data were analyzed from May 2022 to July 2023.

Main outcomes and measures

Clinical outcom

SUBMITTER: Hariri E 

PROVIDER: S-EPMC10716735 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature