Automatic Photo-Cross-Linking System for Robotic-Based In Situ Bioprinting.

ABSTRACT: This work reports the design and validation of an innovative automatic photo-cross-linking device for robotic-based in situ bioprinting. Photo-cross-linking is the most promising polymerization technique when considering biomaterial deposition directly inside a physiological environment, typical of the in situ bioprinting approach. The photo-cross-linking device was designed for the IMAGObot platform, a 5-degree-of-freedom robot re-engineered for in situ bioprinting applications. The system consists of a syringe pump extrusion module equipped with eight light-emitting diodes (LEDs) with a 405 nm wavelength. The hardware and software of the robot were purposely designed to manage the LEDs switching on and off during printing. To minimize the light exposure of the needle, thus avoiding its c

SUBMITTER: Fortunato GM 

PROVIDER: S-EPMC10716819 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature