Genetic analysis and prenatal diagnosis of a pedigree with developmental retardation due to paternal 8q/18q translocation.

ABSTRACT: Balanced reciprocal chromosomal translocation carriers will have greater risk to experience recurrent miscarriages, embryonic death, and infertility. We show the pedigree carrying a paternal karyotype which was reported first. This research helps to better understand the clinical manifestations and prognosis of patients with this rare chromosomal abnormality.

SUBMITTER: Jin C 

PROVIDER: S-EPMC10717177 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature