Impact of Surge Strain and Pandemic Progression on Prognostication by an Established COVID-19-Specific Severity Score.

ABSTRACT:

Importance

Many U.S. State crisis standards of care (CSC) guidelines incorporated Sequential Organ Failure Assessment (SOFA), a sepsis-related severity score, in pandemic triage algorithms. However, SOFA performed poorly in COVID-19. Although disease-specific scores may perform better, their prognostic utility over time and in overcrowded care settings remains unclear.

Objectives

We evaluated prognostication by the modified 4C (m4C) score, a COVID-19-specific prognosticator that demonstrated good predictive capacity early in the pandemic, as a potential tool to standardize triage across time and hospital-surge environments.

Design

Retrospective observational cohort study.

Setting

Two hundred eighty-one U.S. hospitals in an administrative healthcare dataset.

SUBMITTER: Yek C 

PROVIDER: S-EPMC10718382 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature