Benefits, harms and cost-effectiveness of cervical screening, triage and treatment strategies for women in the general population.

ABSTRACT: In 2020, the World Health Organization (WHO) launched a strategy to eliminate cervical cancer as a public health problem. To support the strategy, the WHO published updated cervical screening guidelines in 2021. To inform this update, we used an established modeling platform, Policy1-Cervix, to evaluate the impact of seven primary screening scenarios across 78 low- and lower-middle-income countries (LMICs) for the general population of women. Assuming 70% coverage, we found that primary human papillomavirus (HPV) screening approaches were the most effective and cost-effective, reducing cervical cancer age-standardized mortality rates by 63-67% when offered every 5 years. Strategies involving triaging women before treatment (with 16/18 genotyping, cytology, visual inspection with acetic aci

SUBMITTER: Simms KT 

PROVIDER: S-EPMC10719104 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature