Low levels of free triiodothyronine are associated with risk of cognitive impairment in older euthyroid adults.

ABSTRACT: Accumulated evidence showed that thyroid diseases induced cognitive decline. However, the relationship between thyroid hormones (THs) and cognition in older euthyroid people is still unclear. Our study aimed to estimate the association between THs within the euthyroid range and cognition in community-dwelling older adults in China. Data were extracted from a cohort study on the health status of rural older adults from the Guizhou province in China (HSRO). Serum thyroid-stimulating hormone (TSH), free thyroxine (FT₄), and free triiodothyronine (FT₃) were measured using the electrochemiluminescence immunoassay. Cognitive function was evaluated by the Mini-Mental State Examination (MMSE). Linear regression and a binary logistic regression model were used to explore the r

SUBMITTER: Chen H 

PROVIDER: S-EPMC10719249 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature