Unraveling the genome of Bacillus velezensis MEP₂18, a strain producing fengycin homologs with broad antibacterial activity: comprehensive comparative genome analysis.

ABSTRACT: Bacillus sp. MEP₂18, a soil bacterium with high potential as a source of bioactive molecules, produces mostly C16-C17 fengycin and other cyclic lipopeptides (CLP) when growing under previously optimized culture conditions. This work addressed the elucidation of the genome sequence of MEP₂18 and its taxonomic classification. The genome comprises 3,944,892 bp, with a total of 3474 coding sequences and a G + C content of 46.59%. Our phylogenetic analysis to determine the taxonomic position demonstrated that the assignment of the MEP₂18 strain to Bacillus velezensis species provides insights into its evolutionary context and potential functional attributes. The in silico genome analysis revealed eleven gene clusters involved in the synthesis of secondary metabo

SUBMITTER: Medeot D 

PROVIDER: S-EPMC10719345 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature