Acute Disorders of Consciousness in Pediatric Severe Sepsis and Organ Failure: Secondary Analysis of the Multicenter Phenotyping Sepsis-Induced Multiple Organ Failure Study.

ABSTRACT:

Objectives

Acute disorders of consciousness (DoC) in pediatric severe sepsis are associated with increased risk of morbidity and mortality. We sought to examine the frequency of and factors associated with DoC in children with sepsis-induced organ failure.

Design

Secondary analysis of the multicenter Phenotyping Sepsis-Induced Multiple Organ Failure Study (PHENOMS).

Setting

Nine tertiary care PICUs in the United States.

Patients

Children less than 18 years old admitted to a PICU with severe sepsis and at least one organ failure during a PICU stay.

Interventions

None.

Measurements and main results

The primary outcome was frequency of DoC, defined as Glasgow Coma Scale (GCS) less than 12 in the absence of sedatives during an ICU stay, among children

SUBMITTER: Cheung C 

PROVIDER: S-EPMC10719421 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature