Evaluation of factors associated with recruitment rates in early phase clinical trials based on the European Clinical Trials Register data.

ABSTRACT: Effective participant recruitment is a critical challenge in clinical trials. Inadequate enrollment of participants can precipitate delays, escalated costs, and compromise scientific integrity. Despite its relevance, particularly during the early phases, it persists as an obstacle in the field of clinical research. The primary aim of this study was to analyze the recruitment rates of early-phase clinical trials and evaluate their potential associations with key trial characteristics. Using a descriptive and statistical analysis, a research study was conducted based on the early-phase trials registered at the European Clinical Trials Register (EU-CTR), spanning the timeframe from January 2017 to December 2021. Among the 194 trials examined, we found median recruitment rates of 68%. A more d

SUBMITTER: Moraga Alapont P 

PROVIDER: S-EPMC10719455 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature