The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses.

ABSTRACT: Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid system. While cannabis use is quite prevalent in many individuals afflicted with psychiatric illnesses, there is considerable controversy as to whether cannabis may worsen these conditions or provide some form of therapeutic benefit. The development of pharmacological agents which interact with components of the endocannabinoid system in more localized and discrete ways then via phytocannabinoids found in cannabis, has allowed the investigation if direct targeting of the endocannabinoid system itself may represent a novel approach to treat psychiatric illness without the potential untoward side effects associated with cannabis. Herein we re

SUBMITTER: Hill MN 

PROVIDER: S-EPMC10719691 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature