Inverted U-shaped relationship between coffee consumption and serum uric acid in American chronic kidney disease population.

ABSTRACT:

Objective

The objective of this study was to examine the contentious relationship between coffee consumption and serum uric acid (SUA) levels, specifically within American population with chronic kidney disease (CKD).

Methods

A total of 23,381 participants from the 2001-2018 National Health and Nutrition Examination Survey (NHANES) were selected for inclusion in this investigation. Linear regression models and generalized additive models with smooth curve fitting were employed to analyze the association between log coffee consumption and serum uric acid levels. Furthermore, the robustness of the findings was assessed across diverse populations.

Results

The results of the linear regression analysis indicate a positive and marginally statistically significant (p 

SUBMITTER: Song J 

PROVIDER: S-EPMC10719848 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature