Novel Cu(ii) acidic deep eutectic solvent as an efficient and green multifunctional catalytic solvent system in base-free conditions to synthesize 1,4-disubstituted 1,2,3-triazoles.

ABSTRACT: A novel green Cu(ii)-acidic deep eutectic solvent (Cu(ii)-ADES) bearing copper salt, choline chloride, and gallic acid ([ChCl]₄[2GA-Cu(ii)]) was synthesized and thoroughly specified by physicochemical approaches such as FT-IR, EDX, XRD, Mapping, ICP, and UV-Vis analyses and physicochemical properties. After the detection of authentic data, the central composite design (CCD) was utilized to accomplish the pertaining tests and develop the optimum condition, and, in the following, [ChCl]₄[2GA-Cu(ii)] was applied as a green multifunctional catalytic solvent system in reducing agent-free and base-free condition for the three-component click reaction from sodium azide, alkyl, allyl, ester, and benzyl halide, and terminal alkyne made from amines and caprolactam as a cyclic a

SUBMITTER: Bagherzadeh N 

PROVIDER: S-EPMC10719904 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature