Risk factors for preterm birth: an umbrella review of meta-analyses of observational studies.

ABSTRACT:

Background

Preterm birth defined as delivery before 37 gestational weeks is a leading cause of neonatal and infant morbidity and mortality. The aim of this study is to summarize the evidence from meta-analyses of observational studies on risk factors associated with PTB, evaluate whether there are indications of biases in this literature, and identify which of the previously reported associations are supported by robust evidence.

Methods

We searched PubMed and Scopus until February 2021, in order to identify meta-analyses examining associations between risk factors and PTB. For each meta-analysis, we estimated the summary effect size, the 95% confidence interval, the 95% prediction interval, the between-study heterogeneity, evidence of small-study effects, and evidence of ex

SUBMITTER: Mitrogiannis I 

PROVIDER: S-EPMC10720103 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature