Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection.

ABSTRACT:

Background

Eimeria genus belongs to the apicomplexan parasite phylum and is responsible for coccidiosis, an intestinal disease with a major economic impact on poultry production. Eimeria tenella is one of the most virulent species in chickens. In a previous study, we showed a negative impact of caecal microbiota on the physiopathology of this infection. However, the mechanism by which microbiota leads to the physiopathology remained undetermined. Macrophages play a key role in inflammatory processes and their interaction with the microbiota during E. tenella infection have never been investigated. We therefore examined the impact of microbiota on macrophages during E. tenella infection. Macrophages were monitored in caecal tissues by immunofluorescence staining with KUL01 antibody

SUBMITTER: Tomal F 

PROVIDER: S-EPMC10720127 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature