Olive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease.

ABSTRACT:

Background

Olive oil consumption has been inversely associated with the risk of type 2 diabetes (T2D) and cardiovascular disease (CVD). However, the impact of olive oil consumption on plasma metabolites remains poorly understood. This study aims to identify plasma metabolites related to total and specific types of olive oil consumption, and to assess the prospective associations of the identified multi-metabolite profiles with the risk of T2D and CVD.

Methods

The discovery population included 1837 participants at high cardiovascular risk from the PREvención con DIeta MEDiterránea (PREDIMED) trial with available metabolomics data at baseline. Olive oil consumption was determined through food-frequency questionnaires (FFQ) and adjusted for total energy. A total of 1522 partici

SUBMITTER: Garcia-Gavilan JF 

PROVIDER: S-EPMC10720204 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature