Diverse WGBS profiles of longissimus dorsi muscle in Hainan black goats and hybrid goats.

ABSTRACT:

Background

Goat products have played a crucial role in meeting the dietary demands of people since the Neolithic era, giving rise to a multitude of goat breeds globally with varying characteristics and meat qualities. The primary objective of this study is to pinpoint the pivotal genes and their functions responsible for regulating muscle fiber growth in the longissimus dorsi muscle (LDM) through DNA methylation modifications in Hainan black goats and hybrid goats.

Methods

Whole-genome bisulfite sequencing (WGBS) was employed to scrutinize the impact of methylation on LDM growth. This was accomplished by comparing methylation differences, gene expression, and their associations with growth-related traits.

Results

In this study, we identified a total of 3,269 genes fro

SUBMITTER: Ren Y 

PROVIDER: S-EPMC10720224 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature