Exploring multimorbidity profiles in middle-aged inpatients: a network-based comparative study of China and the United Kingdom.

ABSTRACT:

Background

Multimorbidity is better prevented in younger ages than in older ages. This study aims to identify the differences in comorbidity patterns in middle-aged inpatients from China and the United Kingdom (UK).

Methods

We utilized 184,133 and 180,497 baseline hospitalization records in middle-aged populations (40-59 years) from Shaanxi, China, and UK Biobank. Logistic regression was used to calculate odds ratios and P values for 43,110 unique comorbidity patterns in Chinese inpatients and 21,026 unique comorbidity patterns in UK inpatients. We included the statistically significant (P values adjusted by Bonferroni correction) and common comorbidity patterns (the pattern with prevalence > 1/10,000 in each dataset) and employed network analysis to construct multimorbidity

SUBMITTER: Bao Y 

PROVIDER: S-EPMC10720230 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature